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You are here:Home » Antibodies » Antibodies-Carbohydrates, Glycoproteins » Anti -Siglec 7 (Sialic Acid-binding Immunoglobulin-like Lectin, CDw328)

Anti -Siglec 7 (Sialic Acid-binding Immunoglobulin-like Lectin, CDw328)


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IH FC
Siglec 7 is a type I transmembrane glycoprotein and member of the Siglec (sialic acid binding Ig-like lectin) family, originally identified as an inhibitory NK cell receptor (NKR) and negative regulator of NK activation, attributed to ITIM recruitment of SHP-1 phosphatase. Siglec 7 is expressed predominantly by natural killer cells (NK) and to a lesser extent by monocytes and granulocytes and, like Siglec-5 (CD170), has been shown to bind to sialylated ligands of targets through recognition of sialic acid in both the alpha-2,3- and alpha-2,6- glycosidic linkage.
Catalog #S1013-60P
ApplicationsSuitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested.
Recommended DilutionsFlow Cytometry: 1:100-1:200; 10ul labels 1x10e6 cells in 100ul.
Immunohistochemistry (Frozen): 1:100
Optimal dilutions to be determined by the researcher.
IHC Positive Control TissueFrozen tonsil
Recommended Negative ControlI1904-78R: IgG1 Murine Negative Control
HybridomaX63-Ag8.653 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No9A202
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenMonocyte-derived dendritic cells.
SpecificityRecognizes human Siglec 7.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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