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Anti -SIGLEC11 (Sialic Acid-binding Ig-like Lectin 11, Sialic Acid-binding Lectin 11, Siglec-11, UNQ9222/PRO28718) (PE)
Anti -SIGLEC11 (Sialic Acid-binding Ig-like Lectin 11, Sialic Acid-binding Lectin 11,
Siglec-11, UNQ9222/PRO28718) (PE)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
FC |
|
| Siglecs are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-set domain which mediates sialic acid binding, followed by a varying numbers of Ig-like C2-set domains. Siglec-3 and Siglecs-5-13 constitute the CD33/Siglec-3 related group, which are defined by their sequence homology and differential expression in the hematopoietic system. In humans, Siglec-11 is expressed in tissue macrophages, brain microglia, and inflammatory site monocytes. Strong microglial expression is specific to humans, as it is less prominent or absent in chimpanzees and orangutans. | | | Catalog # | S1013-65B | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Excitation | 488nm | | Emission | 565-605nm | | Storage and Stability | May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE). | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant corresponding to human Siglec-11 expressed in CHO cell line. | | Specificity | Recognizes human Siglec-11. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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