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You are here:Home » Antibodies » Abs to Lectins » Anti -Siglec 11 (Sialic Acid-binding Ig-like Lectin 11, Sialic Acid-binding Lectin 11, Siglec 11, UNQ9222/PRO28718) (PE)

Anti -Siglec 11 (Sialic Acid-binding Ig-like Lectin 11, Sialic Acid-binding Lectin 11,
Siglec 11, UNQ9222/PRO28718) (PE)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified FC
Siglecs are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-set domain which mediates sialic acid binding, followed by a varying numbers of Ig-like C2-set domains. Siglec-3 and Siglecs-5-13 constitute the CD33/Siglec-3 related group, which are defined by their sequence homology and differential expression in the hematopoietic system. In humans, Siglec-11 is expressed in tissue macrophages, brain microglia, and inflammatory site monocytes. Strong microglial expression is specific to humans, as it is less prominent or absent in chimpanzees and orangutans.
Catalog #S1013-65B
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionsFlow Cytometry: Neat. 10ul labels up to 1x10e6 cells.
Optimal dilutions to be determined by the researcher.
Excitation 488nm
Emission 565-605nm
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.025mg/ml
FormSupplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant corresponding to human Siglec-11 expressed in CHO cell line.
SpecificityRecognizes human Siglec-11.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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