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Anti -Specific Intracellular Adhesion Molecule Grabbing Nonintegrin R1 (SIGN-R1)
Anti -Specific Intracellular Adhesion Molecule Grabbing Nonintegrin R1 (SIGN-R1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Purified |
IH FC |
|
| Catalog # | S1013-69 | | Applications | Suitable for use in Flow Cytometry and Immunohistochemistry. Other applications have not been tested. | | Recommended Dilutions | Immunohistochemistry: Frozen 1:25-1:50. | | Optimal dilutions to be determined by the researcher. | | Hybridoma | Hybridization of P3-X63-Ag8.563 myeloma cells with spleen cells from immunized rats. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgM | | Clone No | 8J189 | | Host | Rat | | Source | Mouse | | Concentration | Not determined | | Form | Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide | | Purity | Purified by ammonium sulfate precipitation. | | Immunogen | Isolated C3H thymic stromal cells. | | Specificity | Recognizes mouse SIGN-R1, a C-type lectin that has been identified as a murine homolog of the human CD-SIGN related molecule, L-SIGN. Mouse SIGN-R1 is specifically expressed on marginal zone macrophages in the spleen, medullary and subcapsular sinus macrophages in the lymph nodes, and at lower levels on liver sinusoidal endothelial cells. SIGN-R1 has not been detected on murine dendritic cell populations. Blocks the uptake of neutral polysaccharides by macrophages. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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