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You are here:Home » Antibodies » Abs to Protein Kinase Substrates » Anti -SIRP alpha, CT (Signal Regulatory Protein alpha, SIRPalpha, SIRPA, SIRP, Signal-regulatory Protein alpha-1, Sirp-alpha-1, Signal-regulatory Protein alpha-2, Sirp-alpha-2, Signal-regulatory Protein alpha-3, Sirp-alpha-3, Brain Ig-like Molecule with Tyrosin

Anti -SIRP alpha, CT (Signal Regulatory Protein alpha, SIRPalpha, SIRPA, SIRP,
Signal-regulatory Protein alpha-1, Sirp-alpha-1, Signal-regulatory Protein alpha-2,
Sirp-alpha-2, Signal-regulatory Protein alpha-3, Sirp-alpha-3, Brain Ig-like Molecule with
Tyrosin

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified B
Protein tyrosine phosphatases (PTPases) SHP-1 and SHP-2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP-2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP-2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPa, SHPS-1, MyD-1, BIT and p84. SIRPa is a new gene family containing at least fifteen members. SIRPa is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP-2. SIRPa has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes.
Catalog #S1013-86Z4
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:2000
Optimal dilutions to be determined by the researcher.
Positive ControlTHP-1 whole cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified
ImmunogenSynthetic peptide corresponding to human SIRPa (CT).
SpecificityRecognizes human CT. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSignal-regulatory Protein alpha


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