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You are here:Home » Antibodies » Abs to Sirtuins » Anti -SIRT1 (Sirtuin 1, Sirtuin-1, Sirtuin Type 1, hSIRT1, NAD-dependent Deacetylase Sirtuin-1, hSIR2, SIR2-like Protein 1, SIR2L1)

Anti -SIRT1 (Sirtuin 1, Sirtuin-1, Sirtuin Type 1, hSIRT1, NAD-dependent Deacetylase
Sirtuin-1, hSIR2, SIR2-like Protein 1, SIR2L1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family.
Catalog #S1013-88A10
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:64,000
Western Blot: 0.05-0.2ug/ml, observed in lysates of cell line Jurkat on ~120kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-EKPQEVQTSRNVES, from human SIRT1, at the internal region of the protein (NP_036370.2, NP_001135970.1).
SpecificityRecognizes human SIRT1. Species sequence homology: Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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