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You are here:Home » Antibodies » Abs to Sirtuins » Anti -SIRT1 (NAD-dependent Deacetylase Sirtuin-1, hSIRT1, SIR2-like Protein 1,SIR2L1 Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 1 (S. cerevisiae), hSIR2, SIR2L1) (Azide Free)

Anti -SIRT1 (NAD-dependent Deacetylase Sirtuin-1, hSIRT1, SIR2-like Protein 1,SIR2L1
Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 1 (S. cerevisiae), hSIR2,
SIR2L1) (Azide Free)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IF
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. [provided by RefSeq]
Catalog #S1013-88A6
ApplicationsSuitable for use in Immunofluorescence and Western Blot. Other applications not tested.
Recommended DilutionsWestern Blot: 1:500-1:1000
Immunofluorescence: 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No11C756
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
PurityPurified by immunoaffinity chromatography.
ImmunogenPartial recombinant protein corresponding to a portion of amino acids within aa456-555, from human SIRT1 with GST tag. GST tag alone is 26kD.
SpecificityRecognizes human SIRT1 at ~81kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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