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Anti -SIRT3 (NAD-dependent Protein Deacetylase Sirtuin-3, Mitochondrial, hSIRT3, Regulatory Protein SIR2 Homolog 3, SIR2-like Protein 3, SIR2L3)
Anti -SIRT3 (NAD-dependent Protein Deacetylase Sirtuin-3, Mitochondrial, hSIRT3,
Regulatory Protein SIR2 Homolog 3, SIR2-like Protein 3, SIR2L3)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Silent information regulator (Sir2)-like family deacetylases (also known as sirtuins) are highly conserved proteins and have important roles in the regulation of metabolism, inflammation, cellular survival growth and differentiation. SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Yeast sirtuin proteins are found to regulate epigenetic gene silencing. Sirtuins are NAD-dependent protein ADP-ribosyl transferase which catalyzes the transfer of ADP-ribosyl groups onto target proteins. | | | Catalog # | S1013-88F8 | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 0.5-4ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 5mM EDTA, 0.01% thimerosal, 30% glycerol. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa387 from human SIRT3. | | Specificity | Recognizes human SIRT3. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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