Anti -SIRT 4 (Sirtuin 4, Sirtuin-4, Sirtuin Type 4, MGC57437, MGC130046, MGC130047,
NAD-dependent ADP-ribosyltransferase Sirtuin-4, Sir2 Like 4, Sir2-like 4, SIR2 Like
Protein 4, SIR2-like Protein 4, SIR2L4)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
B |
|
| SIRT4, otherwise known as sirtuin 4, is a mitochondrial NAD-dependent ADP-ribosyl transferase, and member of the sirtuin family, which catalyzes the transfer of ADP-ribosyl groups onto target proteins. Studies have shown that SIRT4 acts as a repressor of GDH (glutamate dehydrogenase) activity in beta cell mitochondria, thereby suppressing amino-acid dependent insulin production. | | | Catalog # | S1013-88H4 | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1-3ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human Kidney lysate | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to SRCGELLPLIDPC, from the C-terminus of the protein sequence according to NP_036372. | | Specificity | Recognizes human SIRT4. Species sequence homology: mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 4 (S. cerevisiae), EC=2.4.2.-, NAD-dependent Deacetylase Sirtuin 4, Silent Mating Type Information Regulation 2 Homolog |
|
|
Questions or comments about this product? Inquire here. |
|
|
Download Specifications for Anti -SIRT 4 (Sirtuin 4, Sirtuin-4, Sirtuin Type 4, MGC57437, MGC130046, MGC130047, NAD-dependent ADP-ribosyltransferase Sirtuin-4, Sir2 Like 4, Sir2-like 4, SIR2 Like Protein 4, SIR2-like Protein 4, SIR2L4) |
External Links
|
