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You are here:Home » Molecular Biology » MB-Sirtuins » SIRT6, Recombinant, Human, GST-Tag (Sirtuin 6, Sirtuin-6, Mono-ADP-ribosyltransferase Sirtuin-6, SIR2-like Protein 6, SIR2L6)

SIRT6, Recombinant, Human, GST-Tag (Sirtuin 6, Sirtuin-6, Mono-ADP-ribosyltransferase
Sirtuin-6, SIR2-like Protein 6, SIR2L6)

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Specifications

Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human ageing.
Catalog #S1013-88L
SourceRecombinant human Sirtuin 6, full length, with N-terminal GST tag, expressed in E. coli.
Molecular Weight 65kD
ApplicationsUseful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityAliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months.
SourceE. coli
Purity75%
ConcentrationAs reported
FormSupplied as a liquid in 25mM Tris-HCl, pH8.0, 100mM NaCl, 0.05% Tween-20, 20% glycerol, 3mM DTT.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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