SIRT6, Recombinant, Human (Sirtuin 6, Sirtuin-6, Mono-ADP-ribosyltransferase Sirtuin-6,
SIR2-like Protein 6, SIR2L6)
Pricing
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| Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human ageing. | | | Catalog # | S1013-88L | | Source | Recombinant human Sirtuin 6, full length, with N-terminal GST tag, expressed in E. coli. | | Molecular Weight | 65kD | | Applications | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months. | | Source | E. coli | | Purity | 75% | | Concentration | As reported | | Form | Supplied as a liquid in 25mM Tris-HCl, pH8.0, 100mM NaCl, 0.05% Tween-20, 20% glycerol, 3mM DTT. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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