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You are here:Home » Antibodies » Abs to Transcription Factors, Homeobox (HOX) » Anti -SIX2 (Sine Oculis Homeobox Homolog 2)

Anti -SIX2 (Sine Oculis Homeobox Homolog 2)


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Clone Host Grade Applications
Monoclonal Rabbit Supernatant B
SIX2 is a member of the vertebrate gene family that is homologous to the Drosophila 'sine oculis' homeobox protein. It is a transcription factor that, like other members of this family, may be involved in limb or eye development (1). SIX2 is expressed in a subset of metanephric mesenchyme, where its expression is maintained throughout kidney development; no expression is detected in adult mouse kidneys (2). Moreover, it is strongly expressed in skeletal muscle (3).
Catalog #S1014-08D
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-10,000
Optimal dilutions to be determined by the researcher.
Positive ControlWestern Blot: Human skeletal muscle, mouse skeletal muscle, rat skeletal muscle, and L6 lysates
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone No11C193
ConcentrationNot determined.
FormSupplied as a liquid in 50mM tris-glycine, pH7.4, 0.15M NaCl, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
ImmunogenSynthetic peptide corresponding to residues in human SIX2.
SpecificityRecognizes human SIX2 at ~32kD. Species Crossreactivity: mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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