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Anti -SLITRK5 (SLIT and NTRK-like Family Member 1, HGNC:20297, KIAA0918, KIAA1910, Leucine-rich Repeat-containing Protein 12, LRRC12, RP11-395N17.1, Slit and trk-like 1 Protein, Slit and Trk-like Gene 1)
Anti -SLITRK5 (SLIT and NTRK-like Family Member 1, HGNC:20297, KIAA0918, KIAA1910,
Leucine-rich Repeat-containing Protein 12, LRRC12, RP11-395N17.1, Slit and trk-like 1
Protein, Slit and Trk-like Gene 1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| SLIT and NTRK-like family 5 (Slitrk5) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains (1). Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family (1,2). Like every other Slitrk protein except Slitrk1, overexpression of Slitrk5 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. This antibody is predicted to have no cross-reactivity to other Slitrk proteins. | | | | | | Applications: | | | Suitable for use in Western Blot. Other applications not tested. | | | Catalog # | S1014-18U1 | | Recommended Dilution | Western Blot: 0.5–1ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to 15aa from near the center of human Slitrk5 (GenBank accession no. O94991). | | Specificity | Recognizes human Slitrk5. Species crossreactivity: Mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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