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You are here:Home » Antibodies » Abs to Smad Proteins » Anti -Smad1 (SMAD Family Member 1, SMAD-1, BSP1, BSP-1, Dwarfin A, DwfA, hSMAD1, hSMAD-1, JV41, JV4-1, MAD Mothers Against Decapentaplegic Homolog 1, Mothers Against Decapentaplegic Homolog 1, Mothers Against DPP Homolog 1, MADH1, Mad-related Protein 1, MADR1,

Anti -Smad1 (SMAD Family Member 1, SMAD-1, BSP1, BSP-1, Dwarfin A, DwfA, hSMAD1, hSMAD-1,
JV41, JV4-1, MAD Mothers Against Decapentaplegic Homolog 1, Mothers Against
Decapentaplegic Homolog 1, Mothers Against DPP Homolog 1, MADH1, Mad-related Protein 1,
MADR1,

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFbeta/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-beta and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFbeta signaling by interfering with TGFbeta-mediated phosphorylation of other Smad family members.
Catalog #S1014-51G
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Numbern/a
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormPhosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to amino acid residues around 253 of human Smad1.
SpecificityThe antibody recognizes ~60kD human Smad1. Reactivity to other species has not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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