Anti -SMAD2 (MADH2, JV18, MADR2, SMAD2, JV18-1, MAD, Mothers Against Decapentaplegic
Homolog 2 (Drosophila), Mothers Against Decapentaplegic, Drosophila, Homolog of, 2, MAD
(Mothers Against Decapentaplegic, Drosophila) Homolog 2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
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| SMAD2 protein (also known as MADH2) is a transcriptional modulator activated by TGF beta. It is found at high levels in skeletal muscle, heart and placenta. SMAD2 exists in isoforms, a predominant long form and a short form missing the 30aa exon 3. The short form shows DNA binding and higher transcriptional activation activity. SMAD2 may act as a tumor suppressor in colorectal carcinoma. | | | Catalog # | S1014-52E3 | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot:1:500-1:1,000 | | Immunohistochemistry:1:50-1:100 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic non-phosphopeptide corresponding to human Smad2 around the phosphorylation site of threonine 220 (P-E-TP-P-P). | | Specificity | Recognizes human Smad2. Species Cross-Reactivity: mouse, rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -SMAD2 (MADH2, JV18, MADR2, SMAD2, JV18-1, MAD, Mothers Against Decapentaplegic Homolog 2 (Drosophila), Mothers Against Decapentaplegic, Drosophila, Homolog of, 2, MAD (Mothers Against Decapentaplegic, Drosophila) Homolog 2) |
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