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You are here:Home » Antibodies » Abs to Smad Proteins » Anti -SMAD3 (Mothers Against Decapentaplegic Homolog 3, Mothers Against DPP Homolog 3, MAD Homolog 3, Mad3, SMAD Family Member 3, SMAD 3, Smad3, JV15-2, MADH3)

Anti -SMAD3 (Mothers Against Decapentaplegic Homolog 3, Mothers Against DPP Homolog 3, MAD
Homolog 3, Mad3, SMAD Family Member 3, SMAD 3, Smad3, JV15-2, MADH3)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Smad3 is a 50kD transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase, functioning in cell proliferation, differentiation and development. Upon stimulation, Smad3 oligomerizes with Smad4 and translocates into the nucleus and binds to DNA and transcription factors.
Catalog #S1014-52X
Smad3 activity induces differentiation of selected neuronal subtypes at the expense of other subtypes.
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:15,000-1:50,000
Western Blot: 1:500-1:1,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.01% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the internal region of human SMAD3.
SpecificityRecognizes human Smad3. Species sequence homology: rat, mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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