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You are here:Home » Antibodies » Abs to Smad Proteins » Anti -SMAD4, phosphorylated (Thr277) (Mothers Against Decapentaplegic Homolog 4, SMAD 4, Mothers Against DPP Homolog 4, Deletion Target In Pancreatic Carcinoma 4, MAD Homolog 4, SMAD Family Member 4, hSMAD4, DPC4, MADH4)

Anti -SMAD4, phosphorylated (Thr277) (Mothers Against Decapentaplegic Homolog 4, SMAD 4,
Mothers Against DPP Homolog 4, Deletion Target In Pancreatic Carcinoma 4, MAD Homolog 4,
SMAD Family Member 4, hSMAD4, DPC4, MADH4)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E IH IF
Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
Catalog #S1014-55C1
ApplicationsSuitable for use in ELISA, Dot Blot, Immunohistochemistry and Immunofluorescence. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Dot Blot: 1:500
Immunohistochemistry: paraffin
Immunofluorescence: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic phosphopeptide corresponding to amino acid residues surrounding Thr277 of human SMAD4 (KLH).
SpecificityRecognizes human SMAD4 when phosphorylated at Thr277.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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