SMAD4, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q13485

Isotype

IgG

Grade

Purified

Applications

E FC IF IHC WB

Crossreactivity

Accession #

NP_005350

Shipping Temp

Blue Ice

Storage Temp

-20°C

SMAD4 is the common SMAD (co-SMAD)mediator of signal transduction by TGF-beta (transforming growth factor). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.

Applications

Suitable for use in ELISA, Western Blot, Immunohistochemistry, Indirect Flow Cytometry and Immunofluorescence . Other applications not tested.

Recommended Dilution

ELISA: 1:1,000 Western Blot: 1:50-1:100 Immunohistochemistry: 1:50-1:100 Indirect Flow Cytometry: 1:10~1:50 Immunofluorescence: 1:10~1:50 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Synthetic peptide selected from the C-terminal region of human SMAD4 (KLH).

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Purity

Purified by ammonium sulfate precipitation.

Specificity

Recognizes human SMAD4.

References

1.Sekiya, T., et al., Biochem. Biophys. Res. Commun. 320(3):680-684 (2004). 2.Horvath, L.G., et al., Prostate 59(3):234-242 (2004). 3.Li, L., et al., Mol. Cell. Biol. 24(2):856-864 (2004). 4.Wan, M., et al., J. Biol. Chem. 279(15):14484-14487 (2004). 5.Maru, D., et al., Oncogene 23(3):859-864 (2004).

USBio References

No references available

Product	Size	List	Your Price	Qty	Ext Price
Subtotal:	Subtotal:
Subtotal:	Subtotal:
Total Coupon Savings:	Total Coupon Savings:	()
Your cart is currently empty.
- Coupon Code

Product

Size

List

Your Price

Qty

Ext Price

Subtotal:

Total Coupon Savings:

()

Your cart is currently empty.

- Coupon Code

S1014-55C3 Rabbit Anti-SMAD4, CT (Mothers Against Decapentaplegic Homolog 4, SMAD 4, Mothers Against DPP Homolog 4, Deletion Target In Pancreatic Carcinoma 4, MAD Homolog 4, SMAD Family Member 4, hSMAD4, DPC4, MADH4)

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Accession #

Shipping Temp

Storage Temp

References

USBio References

Conjugates

Pricing

Order

Cart Summary

Recently Viewed

Special Offers

Contact Us

Site Map

Technical Resources

Distributors

Payment Methods