Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Smad Proteins » Anti -Smad5 (Small Mothers Against Decapentaplegic Deleted in Pancreatic Carcinoma)

Anti -Smad5 (Small Mothers Against Decapentaplegic Deleted in Pancreatic Carcinoma)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IC FC
Smad 5 is a member of the Mothers Against Dpp (MAD)-related family of proteins. So far, eight Smads have been identified and can be divided into 3 subgroups based on their structure and function; pathway-restricted, common mediator and inhibitory. Smad 1, 5 and 8 serve as pathway-restricted Smads for the bone morphogenetic proteins (BMPs) signaling pathway (1). Smad 5 is directly activated by BMP type Ia or Ib receptors upon BMP-2 stimulation and transduced BMP-2 signals to the nucleus by forming a complex with Smad 4 (2-3).
Catalog #S1014-55G2
ApplicationsSuitable for use in Flow Cytometry, Immunocytochemistry and Western Blot. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:30
Immunocytochemistry: 1:50
Western Blot: 1:1,000 -1:10,000 (MW: 52kDa)
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No6k376
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid containing sodium azide, glycerol, and BSA
PuritySupernatant
ImmunogenA synthetic peptide corresponding to residues near the MH2 domain of human Smad 5
SpecificityRecognizes human Smad 5
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links