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Abs to Transcription Factors, Zinc (Ring) Finger
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Anti -Snail Homolog 2 (SNAI2, MGC10182, SLUG, SLUGH, SLUGH1, WS2D)
Anti -Snail Homolog 2 (SNAI2, MGC10182, SLUG, SLUGH, SLUGH1, WS2D)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Purified |
B IH |
|
| This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. | | | Catalog # | S1014-67M | | Applications | Suitable for use in Immunohistochemistry and Western Blot. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry (FFPE): 2.5ug/ml. Requires heat-induced antigen retrieval in pH 6.0 citrate buffer. | | Western Blot: 1-2ug/ml | | Optimal dilution to be determined by researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.02% sodium azide. | | Purity | Purified | | Immunogen | Synthetic peptide corresponding to 13aa near the center of human Slug (KLH). | | Specificity | Recognizes human Snail Homolog 2 (SNAI2). Species sequence homology: mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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