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You are here:Home » Antibodies » Abs to RNA Processing » Anti -SNRPA1 (U2 Small Nuclear Ribonucleoprotein A', U2 snRNP-A')

Anti -SNRPA1 (U2 Small Nuclear Ribonucleoprotein A', U2 snRNP-A')


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E
SNRPA1, a 28kD protein, is a specific component of U2 snRNP particle and consists of a unique N-terminal leucine-rich region and an extremely hydrophobic RNA-binding C-terminal region. It lacks segments homologous to RNP1 and RNP2, common aa motifs found in several RNA-binding proteins. It associates with U2 snRNP and participates in transcription and pre-mRNA splicing. It might play an important role in cell division and proliferation. Patients with connective tissue disorders often produce autoantibodies against snRNP particles.
Catalog #S1014-96H3
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 0.1-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa150-164 of human SNRPA1.
SpecificityRecognizes human SNRPA1. Species sequence homology: mouse, rat, chimpanzee, bovine, chicken.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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