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You are here:Home » Antibodies » Abs to RNA Processing » Anti -SNRPA1 (U2 Small Nuclear Ribonucleoprotein A', U2 snRNP-A')

Anti -SNRPA1 (U2 Small Nuclear Ribonucleoprotein A', U2 snRNP-A')

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E
SNRPA1, a 28kD protein, is a specific component of U2 snRNP particle and consists of a unique N-terminal leucine-rich region and an extremely hydrophobic RNA-binding C-terminal region. It lacks segments homologous to RNP1 and RNP2, common aa motifs found in several RNA-binding proteins. It associates with U2 snRNP and participates in transcription and pre-mRNA splicing. It might play an important role in cell division and proliferation. Patients with connective tissue disorders often produce autoantibodies against snRNP particles.
Catalog #S1014-96H3
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 0.1-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa150-164 of human SNRPA1.
SpecificityRecognizes human SNRPA1. Species sequence homology: mouse, rat, chimpanzee, bovine, chicken.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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