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You are here:Home » Antibodies » Abs to SNX (Sorting Nexin) Proteins » Anti -SNX1 (Sorting Nexin 1, SNX-1, Sorting Nexin 1A, SNX1A, HsT17379, MGC8664)

Anti -SNX1 (Sorting Nexin 1, SNX-1, Sorting Nexin 1A, SNX1A, HsT17379, MGC8664)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
Catalog #S1014-97A6
ApplicationsSuitable for use in ELISA and Western Blot. Other applications have not been tested.
Recommended Dilutions
Peptide ELISA Titer: 1:64,000
Western Blot: 1-3ug/ml ~75kD band observed in Human lysates of cell line HeLa (calculated MW of 59.1kD according to NP_003090.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by peptide affinity chromatography.
ImmunogenSynthetic peptide corresponding to C-TNSSKPQPTYEELE, from the internal region of human SNX1 (NP_003090.2; NP_690039.1).
SpecificityRecognizes human SNX1. Species sequence homology: mouse, rat, canine, bovine. This antibody is expected to recognize isoform a and c (NP_003090.2; NP_690039.1).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesHsT17379, MGC8664, SNX1A, Sorting nexin-1, Vps5


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