Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to SOCS » Anti -SOCS 1, CT (Suppressor of Cytokine Signaling 1, SOCS1, SOCS-1, Cytokine Inducible SH2 Protein 1, CISH1, Janus Kinase Binding Protein, JAK-binding Protein, JAB, STAT-induced STAT Inhibitor 1, SSI1, SSI-1, TEC-interacting Protein 3, TIP3, TIP-3)

Anti -SOCS 1, CT (Suppressor of Cytokine Signaling 1, SOCS1, SOCS-1, Cytokine Inducible
SH2 Protein 1, CISH1, Janus Kinase Binding Protein, JAK-binding Protein, JAB, STAT-induced
STAT Inhibitor 1, SSI1, SSI-1, TEC-interacting Protein 3, TIP3, TIP-3)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Suppressor of cytokine signalling 1 (SOCS1) is a 24kD member of the Suppressor of cytokine signalling family. SOCS1 acts downstream of cytokine receptors and plays a role in the negative regulation of cytokine signalling. It acts mainly on the Janus kinase (JAK)/signal transducers and activators of transcription-3 (STAT3) pathway but also inhibits signalling by cytokines such as insulin and toll-like receptors. Furthermore SOCS1 is involved in ubiquitin-dependent protein degradation, plays a role in T cell activation and in the regulation of IL-6, IL-4, IL-12 and IL-15. SOCS1 is expressed ubiquitously and at elevated levels in the spleen, small intestine and peripheral blood leukocytes.
Catalog #S1040-01Q
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenA 15aa peptide located near the carboxy terminus of human SOCS1.
SpecificityRecognizes human SOCS1. Species Crossreactivity: mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links