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You are here:Home » Biochemicals » Biochem-Molecular Biology » Sodium Butyrate, 1M (Histone Deacetylase Inhibitor)

Sodium Butyrate, 1M (Histone Deacetylase Inhibitor)


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A short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and inteferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protease kinase casein kinase II in HT29 cells.
Catalog #S4600
ApplicationsFor use as a histone deacetylase inhibitor.
Recommended Dilutions1, 5, 20 and 100mM showed >70% inhibition of HDAC activity in HeLa nuclear extract using H5109-62: Histone Deacetylase (HDAC), BioAssay™ Fluorometric Detection Kit.
Optimal dilutions to be determined by the researcher.
Storage and StabilityStore at 4°C. Stable for 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular FormulaC4H7NaO2
Molecular Weight110.09
FormSupplied as a liquid in 1M solution in sterile distilled water.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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