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You are here:Home » Biochemicals » Biochem-Molecular Biology » Sodium butyrate

Sodium butyrate

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Specifications

A short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and inteferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protease kinase casein kinase II in HT29 cells.
Catalog #S4601
ApplicationsSuitable for use as a histone deacetylase inhibitor. Other applications have not been tested
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with sterile ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number156-54-7
Molecular FormulaC4H7O2 . Na
Molecular Weight110.1
Purity~99% by HPLC
FormSupplied as a white solid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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