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You are here:Home » Antibodies » Abs to Spectrin » Anti -Spectrin, alpha, beta (SPTA, SPTB, Spectrin alpha Chain, Erythrocyte, Erythroid alpha-spectrin, SPTA1, Spectrin beta Chain, Erythrocyte, Beta-I Spectrin, SPTB1)

Anti -Spectrin, alpha, beta (SPTA, SPTB, Spectrin alpha Chain, Erythrocyte, Erythroid
alpha-spectrin, SPTA1, Spectrin beta Chain, Erythrocyte, Beta-I Spectrin, SPTB1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2. Spectrin mutations cause spinocerebellar ataxia type 5.
Catalog #S5380-01B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 2-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with 1.2% sodium acetate. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10K346
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from 1.2% sodium acetate, 2mg BSA, 0.01mg sodium azide. Reconstitute with 1.2% sodium acetate, PBS.
PurityPurified by immunoaffinity chromatography.
ImmunogenHuman erythrocyte spectrin.
SpecificityRecognizes human spectrin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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