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You are here:Home » Antibodies » Abs to Spectrin » Anti -Spectrin Beta 3 (Beta III Spectrin, KIAA0302, Spectrin beta Chain Brain 2, Spectrin beta Non-erythrocytic 2, Spectrin Non-erythroid beta Chain 2, SPTBN2, Spinocerebellar Ataxia 5, SCA5, SCA 5)

Anti -Spectrin Beta 3 (Beta III Spectrin, KIAA0302, Spectrin beta Chain Brain 2, Spectrin
beta Non-erythrocytic 2, Spectrin Non-erythroid beta Chain 2, SPTBN2, Spinocerebellar
Ataxia 5, SCA5, SCA 5)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP IH
Mutations in spectrins are a previously unknown cause of ataxia and neurodegenerative disease that affect membrane proteins involved in glutamate signaling. Spectrin-beta IIIs have been recognized as ataxia disease genes and their mutations cause spinocerebellar ataxia type 5 (SCA5).
Catalog #S5380-14
ApplicationsSuitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1
FormTris-citrate/phosphate buffer, pH 7 to 8
PurityPurified by immunoaffinity chromatography.
ImmunogenThe epitope recognized by this antibody maps to a C-terminal region between residue 2300 and 2390 of human spectrin, beta, non-erythrocytic 2 (spinocerebellar ataxia 5 ) using the numbering given in entry NP_008877.1. Homology: 100% with human, mouse, and rat protein.
SpecificitySpecies Crossreactivity: This antibody reacts with human. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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