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Abs to Spectrin
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Anti -Spectrin Beta 3 (Beta III Spectrin, KIAA0302, Spectrin beta Chain Brain 2, Spectrin beta Non-erythrocytic 2, Spectrin Non-erythroid beta Chain 2, SPTBN2, Spinocerebellar Ataxia 5, SCA5, SCA 5)
Anti -Spectrin Beta 3 (Beta III Spectrin, KIAA0302, Spectrin beta Chain Brain 2, Spectrin beta Non-erythrocytic 2, Spectrin Non-erythroid beta Chain 2, SPTBN2, Spinocerebellar Ataxia 5, SCA5, SCA 5)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IP IH |
|
| Mutations in spectrins are a previously unknown cause of ataxia and neurodegenerative disease that affect membrane proteins involved in glutamate signaling. Spectrin-beta IIIs have been recognized as ataxia disease genes and their mutations cause spinocerebellar ataxia type 5 (SCA5). | | | Catalog # | S5380-14A | | Applications | Suitable for use in Immunoprecipitation and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Positive Control | HeLa whole cell lysate | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Tris-citrate/phosphate buffer, pH 7 to 8 | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | The epitope recognized by this antibody maps to a region between residues 2150 and 2200 of human spectrin, beta, non-erythrocytic 2 (spinocerebellar ataxia 5 ) using the numbering given in entry NP_008877.1. Homology: 100% with human, mouse, and rat protein. | | Specificity | Species Crossreactivity: This antibody reacts with human. Other species have not been tested. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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