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Anti -Spectrin, beta 2 (Spectrin beta Chain Brain 2, Spectrin beta Non-erythrocytic 2, SPTBN2, Spectrin Non-erythroid beta Chain 2, Spinocerebellar Ataxia 5, SCA5)
Anti -Spectrin, beta 2 (Spectrin beta Chain Brain 2, Spectrin beta Non-erythrocytic 2,
SPTBN2, Spectrin Non-erythroid beta Chain 2, Spinocerebellar Ataxia 5, SCA5)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IP IH |
|
| Mutations in spectrins are a previously unknown cause of ataxia and neurodegenerative disease that affect membrane proteins involved in glutamate signaling. Spectrin-beta IIs have been recognized as ataxia disease genes and their mutations cause spinocerebellar ataxia type 5 (SCA5). | | | | | | Applications: | | | Suitable for use in Immunohistochemistry and Immunoprecipitation. Other applications not tested. | | | Catalog # | S5380-15 | | Recommended Dilution | Immunohistochemistry: 2.5-5ug/ml | | Immunoprecipitation: 2-5ug/mg lysate | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | The epitope recognized by this antibody maps to a region between residues 2150 and 2200 of human spectrin, beta, non-erythrocytic 2 (spinocerebellar ataxia 5) using the numbering given in entry NP_008877.1 | | Specificity | Recognizes human Spectrin, beta 2. Species Sequence Homology: Mouse and rat - 100%. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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