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You are here:Home » Antibodies » Abs to Spectrin » Anti -Spectrin (Alpha I Spectrin, Alpha-Spec, Beta I Spectrin, Beta Spectrin, Beta-Spec, Elliptocytosis 2, Elliptocytosis-2, EL2, Erythrocyte alpha Spectrin, Erythroid Alpha Spectrin, HSpTB1, Membrane Cytoskeletal Protein, Spec B, Spectrin alpha Chain, Spec A,

Anti -Spectrin (Alpha I Spectrin, Alpha-Spec, Beta I Spectrin, Beta Spectrin, Beta-Spec,
Elliptocytosis 2, Elliptocytosis-2, EL2, Erythrocyte alpha Spectrin, Erythroid Alpha
Spectrin, HSpTB1, Membrane Cytoskeletal Protein, Spec B, Spectrin alpha Chain, Spec A,

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IF
Spectrin is the predominant component of the membrane skeleton of the red blood cell and is essential in determining shape and deformability of the membrane. It consists of 2 nonidentical subunits, alpha (MW 240,000) and beta (MW 225,000). Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head to head self association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2 dimensional network.
Catalog #S5381-03B
ApplicationsSuitable for use in Immunofluorescence and Western Blot. Other applications not tested.
Recommended DilutionsWestern Blot: 1:40. Detects a band at 220kD and 240kD
Immunofluorescence: 1:40
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceChicken
ConcentrationNot Determined
FormSupplied as a liquid, 0.1% sodium azide.
PuritySerum
ImmunogenFull length, purified, native spectrin alpha and beta chain from chicken. Cellular Localization: Cytoplasmic surface of the cell membrane.
SpecificityRecognizes chicken Spectrin. Species Crossreactivity: Crossreacts with a wide range of avian and mammalian species.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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