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Anti -Sptan1 (Spectrin alpha Chain, Non-erythrocytic 1, Alpha-II Spectrin, Fodrin alpha Chain, Spna2, Spta2)
Anti -Sptan1 (Spectrin alpha Chain, Non-erythrocytic 1, Alpha-II Spectrin, Fodrin alpha
Chain, Spna2, Spta2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| Fodrin is a universally expressed membrane-associated cytoskeletal protein consisting of a- and b-subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. a-Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240kD protein can be cleaved at several sites within its sequence by activated caspases generating N-terminal 150kD, C-terminal 120kD, and 35kD major products. Cleavage of a-Fodrin leads to membrane malfunction and cell shrinkage | | | Catalog # | S5381-04A | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 0.5-4ug/ml | | Immunohistochemistry: 10-20ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Mouse | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa162 from mouse alpha-Fodrin. | | Specificity | Recognizes mouse alpha-Fodrin. Species Crossreactivity: human, rat and chicken. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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