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You are here:Home » Antibodies » Antibodies-Spectrin » Anti -Sptan1 (Spectrin alpha Chain, Non-erythrocytic 1, Alpha-II Spectrin, Fodrin alpha Chain, Spna2, Spta2)

Anti -Sptan1 (Spectrin alpha Chain, Non-erythrocytic 1, Alpha-II Spectrin, Fodrin alpha
Chain, Spna2, Spta2)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Fodrin is a universally expressed membrane-associated cytoskeletal protein consisting of a- and b-subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. a-Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240kD protein can be cleaved at several sites within its sequence by activated caspases generating N-terminal 150kD, C-terminal 120kD, and 35kD major products. Cleavage of a-Fodrin leads to membrane malfunction and cell shrinkage
Catalog #S5381-04A
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-4ug/ml
Immunohistochemistry: 10-20ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa162 from mouse alpha-Fodrin.
SpecificityRecognizes mouse alpha-Fodrin. Species Crossreactivity: human, rat and chicken.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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