Anti -EDG8, NT (Sphingosine 1-phosphate Receptor 5, S1P Receptor 5, S1P5, Endothelial
Differentiation G-protein-coupled Receptor 8, Sphingosine 1-Phosphate Receptor Edg-8, S1P
Receptor Edg-8, S1PR5)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E IH |
|
| The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction, both intracellularly as a second messenger and extracellularly as a receptor ligand. EDG8, a receptor for S1P, is a member of the G protein-coupled receptor family, as well as the EDG family of proteins. Human, rat, and mouse EDG8 proteins possess 97% sequence identity and appear to signal via G(i/o)alpha proteins. Human EDG8 is expressed in spleen, corpus collosum, peripheral blood leukocytes, placenta, lung, aorta, and several fetal tissues. Its precise role remains to be determined. | | | Catalog # | S5451-08B | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:1,000 | | Immunohistochemistry: 1:50-1:100 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.25mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide selected from the N-terminal region of human EDG8 (KLH). | | Specificity | Recognizes human EDG8. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
