Stachybotrylactam CAS 163391-76-2

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S6607 Stachybotrylactam (2-deoxy Antibiotic F1839A) CAS: 163391-76-2

Specifications

References

CAS Number

163391-76-2

Grade

Highly Purified

Molecular Formula

C23H31NO4

Molecular Weight

385.5

EU Commodity Code

38220090

Shipping Temp

Blue Ice

Storage Temp

+4°C

2-deoxy Antibiotic F1839A

Isolated from a Stachybotrys sp., this unusual spirodihydrobenzofuranlactam mycotoxin shows immuno-suppressant and weak HIV protease activity. Members of this structural class show diverse activity including antiviral, endothelin and pancreatic cholesterase inhibition.

Purity: >95% by HPLC

Solubility: Soluble in ethanol, methanol, DMF or DMSO.

Source

Stachybotrys sp.

Important Note

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

References

1. Total synthesis and structure revision of Stachybotrys spirolactams. Deng W.P. et al. J. Org. Chem. |2003, 68, 7422. |2. Novel spirodihydrobenzofuranlactams as antagonists of endothelin and as inhibitors of HIV-1 protease |produced by Stachybotrys sp. I. Fermentation, isolation and biological activity. Roggo B.E. et al. J. |Antibiot. 1996, 49, 13. |3. Stachybotrys toxins I. Jarvis B.B. et al. Nat. Toxins 1995, 3, 10.