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Anti -SI-CLP (Stabilin-1-Interacting Chitinase-Like Protein, Chitinase Domain-Containing Protein 1, CHID1, GL008, PSEC0104, SB139)
Anti -SI-CLP (Stabilin-1-Interacting Chitinase-Like Protein, Chitinase Domain-Containing
Protein 1, CHID1, GL008, PSEC0104, SB139)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
B FC IF |
|
| Stabilin-interacting chitinase like protein (SI-CLP), a novel member of the Glyco_18-domain containing protein family. SI-CLP is a secretory protein which is up-regulated in response to interleukin-4 and dexamethasone in alternatively activated macrophages. SI-CLP is also expressed by T- and B-lymphocytes, and by cells of monocytic and epithelial origin. SI-CLP is the ligand for stabilin-1, an intracellular sorting receptor which sorts SI-CLP into late endosomes and secretory lysosomes in activated macrophages. | | | Catalog # | S7950-56 | | Applications | Suitable for use in Flow Cytometry, Immunofluorescence, and Western Blot. Other applications not tested. | | Recommended Dilutions | Flow Cytometry: 10ul labels 10e6 cells in 100ul | | Membrane permeabilisation is required. | | Western Blot: Detects a band at ~33 and 39kD in U937 cell lysates. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 10F432 | | Host | Rat | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | SI-CLP fragment corresponding to aa24-73 expressed as a GST fusion protein in E.coli. | | Specificity | Recognizes human SI-CLP. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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