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You are here:Home » Antibodies » Abs to Adapter Proteins » Anti -STAM2 (Signal Transducing Adapter Molecule 2, STAM-2, Hrs-binding Protein, HBP)

Anti -STAM2 (Signal Transducing Adapter Molecule 2, STAM-2, Hrs-binding Protein, HBP)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
STAM2 (signal transducing adapter molecule 2), a ubiquitously expressed protein and member of the STAM family, involved in cytokine-mediated signal transduction, downstream of JAK kinases. STAM2 is involved in mediating the endocytic sorting of ubiquitinated membrane proteins on early endosomes, binding directly with ubiquitin, and co-localizing with Hrs (hepatocyte growth factor-regulated tyrosine kinase substrate) and Eps15 (epidermal growth factor receptor substrate 15), in clathrin-containing endosomal microdomains.
Catalog #S7954-10C
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:8000
Western Blot: 1-3ug/ml, observed in human spleen lysates on ~70kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-QSIDPTDSKPDSQD, from human STAM2, at the internal region of the protein (NP_005834.3).
SpecificityRecognizes human STAM2. Species sequence homology: Canine and mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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