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You are here:Home » Antibodies » Abs to Transcription Factors, STAT » Anti -STAT 1 (Signal Transducer And Activator Of Transcription 1-alpha/beta, Transcription Factor ISGF-3 Components p91/p84)

Anti -STAT 1 (Signal Transducer And Activator Of Transcription 1-alpha/beta, Transcription
Factor ISGF-3 Components p91/p84)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP IH
STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. STAT1 is involved in the TNFR1-TRADD signaling complex. In Hela cells STAT1 acts as a TNFR1-signaling molecule to suppress NF-kB activation. It has also been shown that its activation slows growth and promotes apoptosis. Human STAT1 gene is mapped to chromosome 2q32.2.
Catalog #S7969-06V
ApplicationsSuitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone NoSM1
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 15mM sodium azide, pH 7.4.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa721-733 from human STAT1 (KLH).
SpecificityRecognizes human STAT1. Species sequence homology: Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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