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You are here:Home » Antibodies » Abs to Transcription Factors, STAT » Anti -STAT2 (Signal transducer and activator of transcription 2, ISGF-3, MGC59816, p113, P113, Signal transducer and activator of transcription 2, STAT113)

Anti -STAT2 (Signal transducer and activator of transcription 2, ISGF-3, MGC59816, p113,
P113, Signal transducer and activator of transcription 2, STAT113)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Signal transducer and activator of transcription 2 (STAT2) is a member of the transcription factor
STAT family with an apparent M.W. of 113kD in SDS-PAGE gels. Human STAT2 is 851aa in length and contains one SH2 domain (aa572-667). Splicing variants produce two isoforms for human STAT2. The short isoform has a 32aa substitution and a 199aa deletion corresponding to aa 621-652 and aa653-851 in the long isoform, respectively. Human STAT2 shares 73% and 65% aa sequence identity with rat and mouse STAT2, in that order. STAT2 functions as a signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta), and it is also required for myogenic differentiation.
Catalog #S7969-83B
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot:1:500-1:1,000
Immunohistochemistry:1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic non-phosphopeptide corresponding to human stat2 around the phosphorylation site of tyrosine 690 (R-K-YP-L-K).
SpecificityRecognizes human STAT2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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