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You are here:Home » Antibodies » Abs to Transcription Factors, STAT » Anti -STAT 2 (Signal Transducer and Activator of Transcription 2, p113, STAT 2)

Anti -STAT 2 (Signal Transducer and Activator of Transcription 2, p113, STAT 2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases, which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and STAT2 are induced by IFN-a and form a heterodimer, which is part of the ISGF3 transcription factor complex.
Catalog #S7969-83F
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 1:50 for 30min at RT
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10min followed by cooling at RT for 20min
Optimal dilutions to be determined by the researcher.
Positive ControlRamos cells, breast carcinoma
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the aa832-851 from human STAT2.
SpecificityRecognizes human STAT2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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