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You are here:Home » Antibodies » Abs to Transcription Factors, STAT » Anti -STAT3, CT (Signal Transducer and Activator of Transcription 3, Acute-phase Response Factor, APRF, FLJ20882, MGC16063)

Anti -STAT3, CT (Signal Transducer and Activator of Transcription 3, Acute-phase Response
Factor, APRF, FLJ20882, MGC16063)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
STAT3 is an 80-85kD member of the STAT protein family, plays an important role in cell growth, survival differentiation and transformation, transducing signals from cytokine receptors to the nucleus. STAT3 is phosphorylated in response to cytokines and growth factors including interleukin-5, interleukin-6, epidermal growth factor and leukemia inhibitory factor. It is expressed in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Catalog #S7971-01W1
ApplicationsSuitable for use in ELISA, Immunohistochemistry (frozen), and Western Blot. Other applications not tested.
Recommended DilutionImmunohistochemistry (frozen): 10ug/ml
ELISA: 1:32,000
Western Blot: 0-5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in tris-saline, pH 7.3, 0.02% sodium azide, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenPeptide sequence DMELTSECARSPM corresponding to the C-terminal region of STAT3 (NP_003141.2; NP_644805.1)
SpecificityRecognizes an epitope within the C-terminal (CT) region of human STAT3. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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