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You are here:Home » Antibodies » Antibodies-Transcription Factors, STAT » Anti -STAT 4 (Signal Transducer and Activator of Transcription 4, STAT4)

Anti -STAT 4 (Signal Transducer and Activator of Transcription 4, STAT4)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
The STAT 4 protein is a transcription factor activated by hormone and cytokines. STAT 4 is most similar to STAT 1 (52%) and STAT 3 (47%). Functionally STAT 4 is similar to other STAT family members in that it can be tyrosine phosphorylated by JAK 1 or JAK 2. STAT 4 forms homodimers and heterodimers with related STAT family members. Tyrosine phosphorylated STAT 4 can bind the interferon g activated site (GAS), and serine phosphorylation is also required for maximal transcriptional activity. STAT 4 expression is restricted to the thymus, spleen, and testis.
Catalog #S7972-02H
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionsWestern Blot:1:500-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 0.02% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography
ImmunogenSynthetic non-phosphopeptide corresponding to human STAT4 around the phosphorylation site of tyrosine 693 (K-G-YP-V-P).
SpecificityRecognizes endogenous levels of total human STAT 4. Species Crossreactivity: mouse and rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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