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You are here:Home » Antibodies » Abs to Transcription Factors, STAT » Anti -STAT 5a,b (Signal Transducer and Activator of Transcription 5a,b)

Anti -STAT 5a,b (Signal Transducer and Activator of Transcription 5a,b)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Two highly related, but distinct Stat5 genes (Stat5a and Stat5b) were identified in mice. The amino acid sequences of Stat5a and Stat5b show ~96% sequence similarity, and both proteins are coexpressed in most tissues of both virgin and lactating mice. However, differential accumulation of Stat5a and Stat5b mRNA has been reported for both muscle and mammary tissue. Stat5 has been shown to be the essential mediator of prolactin induced milk protein gene activation.
Catalog #S7972-11D
Epitope aa371-389 of human Stat5
ApplicationsWestern Blot: (Ab 2-4ug/ml for 2hrs at RT)
Positive Control A431 cells
Cellular Localization Nuclear
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA and 0.09% sodium azide. Also available without BSA and azide. See S7972-11D.
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide aa371-389 from human STAT5.
SpecificityRecognizes STAT5a/b. Species Crossreactivity: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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