Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Transcription Factors, STAT » Anti -STAT 6 phosphorylated (Y641) (STAT6B, STAT6C, D12S1644, IL-4-STAT, interleukin 4 induced STAT, Signal Transducer and Activator of Transcription 6) (BSA & Azide Free)

Anti -STAT 6 phosphorylated (Y641) (STAT6B, STAT6C, D12S1644, IL-4-STAT, interleukin 4
induced STAT, Signal Transducer and Activator of Transcription 6) (BSA & Azide Free)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP
STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Stat6 is rapidly tyrosine phosphorylated following stimulation of appropriate cell lines with IL-3, IL-4, epidermal growth factor (EGF), but is not detectably phosphorylated following stimulation with IL-2, IL-12, or erythropoietin.
Catalog #S7972-26C1
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml
Immunoprecipitation: 1-2ug/ml
Optimal dilution to be determined by researcher.
Recommended Positive ControlNIH 3T3 cells treated with either anisomycin (10ug/ml) or EGF (100ng/ml)
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No4H253
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS. No stabilizing proteins added. No preservative added. Also available with BSA and Azide. See S7972-26C.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to amino acids 631-645 containing a phospho-tyrosine residue of human Stat6.
SpecificityRecognizes human STAT 6 (Signal Transducers and Activators of Transcription 6), phosphorylated (Y641). Species Cross Reactivity: Mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links