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You are here:Home » Antibodies » Abs to Transcription Factors, STAT » Anti -STAT 6 (aa650-670) (Signal Transducer and Activator of Transcription 6)

Anti -STAT 6 (aa650-670) (Signal Transducer and Activator of Transcription 6)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B
STATs (signal transducing activators of transcription) are mediators involved in cytokine signaling. Being the principle substrates of JAK kinases, phosphorylated STATs form head-to-tail homodimers. In response to a specific cytokine signal, STATs move to the nucleus and induce transcription. STAT6 is activated primarily by IL-4 and IL-13.
Catalog #S7972-40H
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1ug/ml for HRP/ECL detection
ELISA: 0.05ug/ml
Optimal dilutions to be determined by the researcher.
Positive Control (supplied)Cell lysate of 2 x 10e6 untreated HepG2 cells. Supplied as a lyophilized powder. Reconstitute with 200ul sterile ddH2O.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with sterile ddH2O, sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9L665
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from 2X PBS, PEG, sucrose, 0.09% sodium azide. Reconstitute with 1ml sterile, ddH2O.
PurityPurified by thiophilic adsorption and size exclusion chromatography.
ImmunogenSynthetic peptide derived from human STAT6 (aa630-650).
SpecificityRecognizes human STAT6 at ~97kD. Species Crossreactivity: mouse, canine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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