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You are here:Home » Antibodies » Abs to Transcription Factors, STAT » Anti -STAT 6, Phosphorylated (Tyr641) (Signal Transducer and Activator of Transcription 6, Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced, Signal Transducer And Activator Of Transcription 6 Nirs Variant 1, STAT6, D12S1644, IL-4 STAT, I

Anti -STAT 6, Phosphorylated (Tyr641) (Signal Transducer and Activator of Transcription 6,
Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced, Signal
Transducer And Activator Of Transcription 6 Nirs Variant 1, STAT6, D12S1644, IL-4 STAT, I

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B
STATs (signal transducing activators of transcription) are mediators involved in cytokine signaling. In response to a specific cytokine signal, STATs move to the nucleus and induce transcription. STAT6 is activated primarily by IL-4 and IL-13. Upon activation, STAT6 is phosphorylated at Tyrosine 641 by Janus Kinases (JAK). Phosphorylated STAT6 forms head-to-tail heterodimers and translocates to the nucleus where it participates in transcriptional control.
Catalog #S7972-40J
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1ug/ml for HRP/ECL detection
ELISA: 0.05ug/ml
Optimal dilutions to be determined by the researcher.
Positive Control (supplied)Cell lysate of 2 x 10e6 IL-4 treated HepG2 cells. Supplied as a lyophilized powder. Reconstitute with 200ul sterile ddH2O.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with sterile ddH2O, sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9L666
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from 2X PBS, PEG, sucrose, 0.09% sodium azide. Reconstitute with 1ml sterile, ddH2O.
PurityPurified by thiophilic adsorption and size exclusion chromatography.
ImmunogenPhosphopeptide.
SpecificityRecognizes activated human STAT6 phosphorylated at Tyrosine 641 at ~97kD. The antibody does not cross react with the non-phosphorylated form of STAT6 nor with unrelated phosphorylation sites.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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