Anti -STMN1 (Stathmin, Leukemia-associated Phosphoprotein p18, Metablastin, Oncoprotein
18, Op18, Phosphoprotein p19, pp19, Prosolin, Protein Pr22, pp17, C1orf215, LAP18, OP18)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
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| Stathmin 1, a neuron-enriched soluble phosphoprotein is a ubiquitous, phylogenetically conserved protein present in the cytoplasm of cells in a variety of unphosphorylated and phosphorylated forms. Stathmin 1 is widely expressed in organisms ranging from Drosophila to humans and is especially highly expressed in the developing nervous system. Its expression is also elevated in a number of leukemias and solid tumors, which has led to the suggestion that it may be involved in tumorigenesis. The protein destabilizes microtubules and increases the frequency by which microtubule plus ends switch from growth to rapid shortening and thus plays an important role in linking cell signaling to the regulation of microtubule dynamics. Human Stathmin 1 has been mapped to chromosomal region 1p36.1-p35. | | | Catalog # | S7972-51N | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:1000 | | Western Blot: 1-3ug/ml, observed in human testes and mouse brain lysates on ~17kD bands | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to C-KNKESKDPADETEAD, from STMN1, at C-terminal (NP_005554.1, NP_981944.1, NP_981946.1). | | Specificity | Recognizes human STMN1. Species Crossreactivity | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -STMN1 (Stathmin, Leukemia-associated Phosphoprotein p18, Metablastin, Oncoprotein 18, Op18, Phosphoprotein p19, pp19, Prosolin, Protein Pr22, pp17, C1orf215, LAP18, OP18) |
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