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You are here:Home » Antibodies » Abs to Adapter Proteins » Anti -STE20-related Kinase Adapter Protein alpha (STE20-related Kinase Adaptor alpha, STRAD alpha, STRADA, STRAD, FLJ90524, LYK5, NY-BR-96, PMSE, Serologically Defined Breast Cancer Antigen, STE20-related Adapter Protein, Stlk)

Anti -STE20-related Kinase Adapter Protein alpha (STE20-related Kinase Adaptor alpha,
STRAD alpha, STRADA, STRAD, FLJ90524, LYK5, NY-BR-96, PMSE, Serologically Defined Breast
Cancer Antigen, STE20-related Adapter Protein, Stlk)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Members of STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. STRAD is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.
Catalog #S7972-73D
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlA549
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by Protein G affinity Chromatography.
ImmunogenSynthetic peptide corresponding to aa300-350 of human STRAD (isoform 1).
SpecificityRecognizes human STE20-related adaptor protein/STRAD. Species sequence homology: mouse, rat, canine, bovine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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