Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications Polyclonal Chicken Affinity Purified B

14-3-3 varsigma/Stratifin was first identified as an epithelial cell antigen (HME-1) exclusively expressed in epithelia. However, the functional role of varsigma in cell proliferation and apoptosis would suggest that this protein could be relevant to the regulation of growth and differentiation of multiple cell types. Recent evidence demonstrates that varsigma acts as a tumor suppressor gene that is inactivated by methylation of its 5’ CpG islands in epithelial tumor cells. In normal epithelia, varsigma is commonly unmethylated.
Catalog #	S7973-69A
Applications	Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution	Western Blot: 1:2000
	Optimal dilutions to be determined by the researcher.
Recommended Secondary Antibodies	I1906 IgY, Chicken Pab Rb x Ch
	I1906-10 IgY, Chicken-HRP Rb x Ch
	I1906-12 IgY, Chicken-FITC Rb x Ch
	I1906-14 IgY, Chicken-AP Rb x Ch
Storage and Stability	For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgY
Host	Chicken
Source	Human
Concentration	~1mg/ml
Form	Supplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free.
Purity	Purified by immunoaffinity chromatography.
Immunogen	Synthetic peptide corresponding to aa1-248 of human Stratifin. MW: 27.77kD
Specificity	Recognizes human Stratifin. Species Crossreactivity: Mouse and rat.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.