Streptococcal Pyrogenic Exotoxin A (SpeA) is a causative agent of the symptoms associated with scarlet fever, has been associated with streptococcal toxic shock-like disease and may play a role in the early events of rheumatic fever.
Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
Streptococcal Pyrogenic Exotoxin A (SPEA).
Form
Supplied as a lyophilized powder from 0.01M phosphate, 0.9% sodium chloride, pH 7.4. No preservative added. Reconstitute with 1ml of deionized water.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes Streptococcal Pyrogenic Exotoxin A (SPEA). Minimal cross-reactivity with staphylococcal enterotoxins A through E, ET, TSST and alpha hemolysin and streptococcal pyrogenic exotoxins B and C.