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Streptonigrin (Bruneomycin, Nigrin, Rufocromomycin, Valacidin, Antibiotic RP 5278)
Streptonigrin (Bruneomycin, Nigrin, Rufocromomycin, Valacidin, Antibiotic RP 5278)
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| Catalog # | S7975-09 | | Streptonigrin is an unusual aminoquinone with broad biological activity against bacteria, fungi, nematodes, viruses and tumor cells. Streptonigrin acts as a bioreductive agent, highly dependent on interactions with metal ions, notably iron, and plays an important role in free radical production through redox cycling of NAD(P)H | quinone oxidoreductase (NQO1). | | Source | Streptomyces sp. MST-AS5763 | | Apperance | Brown black solid | | Solubility | Soluble in DMSO. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | 3930-19-6 | | Molecular Formula | C25H22N4O8 | | Molecular Weight | 506.5 | | Source | Streptomyces sp. MST-AS5763 | | Purity | ~95% by HPLC | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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