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You are here:Home » Molecular Biology » Growth Factors-SDF » Stromal Cell Derived Factor 1alpha, aa1-68, Recombinant, Mouse (SDF1 alpha, SDF1a, SDF-1a, Chemokine (C-X-C Motif) Ligand 12, CXCL12, hIRH, Pre-B cell Growth-stimulating Factor, PBSF, SCYB12, TLSF-a, TPAR1)

Stromal Cell Derived Factor 1alpha, aa1-68, Recombinant, Mouse (SDF1 alpha, SDF1a, SDF-1a,
Chemokine (C-X-C Motif) Ligand 12, CXCL12, hIRH, Pre-B cell Growth-stimulating Factor,
PBSF, SCYB12, TLSF-a, TPAR1)

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Specifications

Chemokine SDF-1 is highly conserved among species and belongs to a large family of small, structurally related cytokines. It is a chemoattractant for T lymphocytes, monocytes, and hemopoietic stem cells and is constitutively expressed in bone-marrow-derived stromal cells. Recent reports indicate that SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. SDF-1a and SDF-1b, are generated by alternative RNA splicing of transcripts encoded by a single gene. SDF-1a differs from SDF-1b by four C-terminal amino acid residues absent in SDF-1a. As yet, no functional differences have been reported.
Catalog #S7975-51
Stromal Cell-Derived Factor-1a (SDF1a) is a recently discovered protein belonging to the a-chemokine (C-X-C) family of cytokines. Murine SDF1a is an 7.9kD protein containing 68 amino acid residues.
Source E. coli
Form Sterile-filtered solution was lyophilized from 10mM acetic acid.
Purity 98% by SDS-PAGE and HPLC analyses.
Endotoxin 0.1 ng/ug
Storage and Stability Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile distilled water and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Biological Activity Determined by its ability to chemoattract human peripheral blood monocytes using a concentration of 50-100ng/ml.
Concentration Range for most in vitro applications 0.1-1 mg/ml
AA Sequence KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK
Country of Origin USA
Molecular Weight7.9kD
SourceHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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