Stromal Cell Derived Factor 1 alpha, Recombinant, Mouse (SDF1 alpha, SDF1a, SDF-1a,
Chemokine (C-X-C Motif) Ligand 12, CXCL12, hIRH, Pre-B cell Growth-stimulating Factor,
PBSF, SCYB12, TLSF-a, TPAR1)
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| SDF-1 alpha, otherwise known as CXCL12a, is a stromal cell derived CXC chemokine which, together with SDF-1 beta, arises from alternative splicing of the SDF-1 gene, and acts as a chemoattractant for T and B lymphocytes, monocytes and migratory neurons. SDF-1 binds with high-affinity to the G protein–coupled receptor CXCR4 (fusin), and acts as an inhibitor of the CXCR4-mediated entry of HIV-1 virus into target T-cells. | | | Catalog # | S7975-51D | | Source | E. coli | | Applications | Suitable for use in Functional Assays. Other applications not tested. | | Biological Activity | Determined by its ability to chemoattract human peripheral blood monocytes, using a concentration of 50-100ng/ml. | | Endotoxin | 1EU/ug | | Molecular Weight | 7.9kD (68 amino acid residue homodimer) | | Storage and Stability | Lyophilized powder may be Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer stored at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Source | E. coli | | Purity | 98% (SDS PAGE and HPLC). | | Concentration | ~0.1mg/ml | | Form | Supplied as a lyophilized powder. No stabilizing proteins added. No preservative added. Reconstitute in 100ul distilled water. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Stromal Cell Derived Factor 1 alpha, Recombinant, Mouse (SDF1 alpha, SDF1a, SDF-1a, Chemokine (C-X-C Motif) Ligand 12, CXCL12, hIRH, Pre-B cell Growth-stimulating Factor, PBSF, SCYB12, TLSF-a, TPAR1) |
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