Stromal Cell Derived Factor 1beta, aa1-72, Recombinant, Human (SDF1b, CXCL12b, Pre-B Cell
Growth-stimulating Factor, PBSF, hIRH, Chemokine (C-X-C Motif) Ligand 12b, TPAR1, SCYB12,
TLSF-b)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Chemokine SDF-1 is highly conserved among species and belongs to a large family of small, structurally related cytokines. It is a chemoattractant for T lymphocytes, monocytes, and hemopoietic stem cells and is constitutively expressed in bone-marrow-derived stromal cells. Recent reports indicate that SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. SDF-1a and SDF-1b, are generated by alternative RNA splicing of transcripts encoded by a single gene. SDF-1a differs from SDF-1b by four C-terminal amino acid residues absent in SDF-1a. As yet, no functional differences have been reported. | | | Catalog # | S7975-61 | | Stromal Cell-Derived Factor-1beta (SDF1b) is a recently discovered protein belonging to the a-chemokine (C-X-C) family of cytokines. Human SDF1b is an 8.5kD protein containing 72 amino acid residues. | | Source | E. coli | | Form | Lyophilized protein without additives. | | Stability | Lyophilized SDF1b, though stable at room temperature, is best stored desiccated below 0°C. Reconstituted human SDF1b should be stored in working aliquots at -20°C. | | Purity | 98% by SDS-PAGE and HPLC analyses. | | Endotoxin | 0.1ng/ug | | Reconstitution | Lyophilized SDF1b is soluble in water and most aqueous buffers. The lyophilized protein can be reconstituted in water to a concentration of 0.1-1mg/ml. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum. | | Biological Activity | Determined by its ability to chemoattract human peripheral T cells activated with PHA and IL-2 using a concentration range of 20-80ng/ml. | | Concentration Range for most in vitro applications | 0.1-1mg/ml | | AA Sequence | KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRF KM | | Country of Origin | USA | | Molecular Weight | 8.5kD | | Source | Human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
|
|
Questions or comments about this product? Inquire here. |
|
|
Download Specifications for Stromal Cell Derived Factor 1beta, aa1-72, Recombinant, Human (SDF1b, CXCL12b, Pre-B Cell Growth-stimulating Factor, PBSF, hIRH, Chemokine (C-X-C Motif) Ligand 12b, TPAR1, SCYB12, TLSF-b) |
External Links
|
